I have used EV tubeless wheels on my '76 Convert, Lesters on my EV, and snowflakes on a Jackal. (notice I'm always moving to tubeless from tubes). Front wheels are easier to convert than rears, because while you can adapt almost anything to a spool axle, you need an actual Guzzi wheel for the driven rear. Because of the set rear caliper mount, you also need to make the fit by modifying the rear rotor and carrier for offset and diameter. So while it can be done, you need to do your homework first to decide if the hassle is worth it. Personally, I think it is.
You aren't married to the Brembo brakes, either. With a spacer/adapter you can chuck up many different brands and types of calipers. I'm currently running Tokico calipers against Honda rotors on a Lester mag with a Nissan master cylinder and linked brake system. The trike has Lesters all the way 'round with Ford disks on the rear and the dual Honda disks on the front. The Honda rotors were needed to get the 320mm diameter I wanted in an offset I could match to spacers to fit the Unit leading link fork and still clear the spokes with the caliper. That's to illustrate that the mod sometimes requires different hub spacers, axle spacers, and rotors to make the fit, but fit it does.
It took some time to really get the combination correct, but Sat night I did a full panic stop from 50mph when I got distracted on a freeway off ramp and found myself facing a hard 90º right turn marked 10mph, ending at an arterial intersection. It was backstopped with a 6" curb and well marked by the tires and debris of others in my situation. I reacted with all the brakes I could muster, and got a satisfying haul-down with all three wheels finally locking when the speed had bled off. The squeal was smooth sounding and the front end did not dive or hop. In much less time than it takes to tell the tale, I was off the brakes and into that 90º turn as though I'd meant to do it that way. I glanced behind me and could see the three tire marks. The offset and even lengths told me all three brakes were working together evenly.
My point is that it takes some fitting, but any swap is possible, and the results can be effective and safe. I'm willing to put in the effort to get away from 40 wire spokes and tubes. Done right, I don't see a downside.
