For me, road bikes used for touring will have a centerstand and tubeless tires. And I carry a slime pump and plug kits. Have had to use them several times, but never on my own bike??? May of just jinxed myself, but it is a weird phemon. I've found nails in tubeless tires found after I got home, though.
I do always try to ride in tire paths and not down the center of the lane or get to close to the center of edge, even when carving curves hitting apexes (that's saved for the track days that are now well in the past).
I've pinched quite a few tubes during tire changes and a several times riding off road when the tires are aired down and landing hard on rocks. Have had to lay the bike on it's side more than once to get the wheel off.