Wired detectors with battery backup means they are normally house powered and all alarm when one trips. Depending on what kind they are photo electric or ionization they can be nuisance tripped by spiders, bugs, dust. But the real problem sounds like they have aged out. I think most will have a date at which they expire, used to be ten years for most. 16 years out you should be considering changing them all. Old ones should be recycled properly as they contain radioactive material.